| Accession |
PRJCA023527 |
| Title |
Exosomes derived from human urine derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
Human intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is nucleus pulposus cell (NPC) degeneration, which contributes to excessive endoplasmic reticulum stress in the intervertebral disk. However, the mechanisms underlying IVDD and NPC degeneration remain unclear. |
| Sample scope |
Monoisolate |
| Release date |
2024-02-18 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38997667
|
Exosomes derived from human urine-derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration
|
BMC Musculoskeletal Disorders
|
10.1186/s12891-024-07636-2
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Scientific Research Project funded by Shanghai Fifth People
|
|
2020WYZT01
|
|
| Natural Science Research Funds of Minhang District, Shanghai
|
|
2022MHZ073
|
|
|
|
| Submitter |
Minghai
Wang (wmhspine@163.com)
|
| Organization |
Shanghai Fifth People's Hospital |
| Submission date |
2024-02-07 |
