项目编号 PRJCA023981
项目标题 Genomics Evolution of Precancerous Lesions in Human Colorectal Cancer
涉及领域 Evolution
数据类型 Whole genome sequencing
Exome
Genome sequencing
物种名称 Homo sapiens
描述信息 This study mainly explores the genetic mechanism and dynamic evolution of precancerous leisions transforming into human colorectal cancer. We screen and collect normal tissues, accompanying precancerous lesions (known as polyps at different stages), and tumor tissues from 107 patients with primary colorectal cancer. Taken advantage of the experimental techniques (genetic sequencing, etc) as well as multidisciplinary approach, we will comprehensively explore the molecular mechanisms and evolutionary patterns of malignant transformation of human precancerous lesions. This will provide new insights for the early prevention, diagnosis, and treatment strategies of colorectal cancer.
样品范围 Multiisolate
发布日期 2024-08-06
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
41292759 Polyclonal origins of human premalignant colorectal lesions bioRxiv 10.1101/2025.09.08.674484 2025
实验材料提供者 Zheng Hu
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 2021YFA1302500
National Natural Science Foundation of China (NSFC) 32270693
National Natural Science Foundation of China (NSFC) 82241236
提交者 Zheng Hu (zheng.hu@siat.ac.cn)
提交单位 Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
提交日期 2024-02-29

项目包含数据信息

资源名称 描述
BioSample (576)  show -