Accession

PRJCA024275

Title

Immune Profiling of the Macroenvironment in Colorectal Cancer Unveils Systemic Dysfunction and Plasticity of Immune Cells

Relevance

Medical

Data types

Phenotype or Genotype
Transcriptome or Gene expression
Single cell sequencing

Organisms

Homo sapiens

Description

Applying single-cell and spaial omics to reveal immune profile of macroenvironment in human colorectal cancer andalteration after anti-PD-1 therapy.

Sample scope

Single cell

Release date

2024-12-31

Publication

PubMed ID	Article title	Journal name	DOI	Year
39934971	Immune profiling of the macroenvironment in colorectal cancer unveils systemic dysfunction and plasticity of immune cells	Clinical and Translational Medicine	10.1002/ctm2.70175	2025

Grants

Agency	program	Grant ID
National Natural Science Foundation of China (NSFC))	Key Program	2022YFA1304000
National Natural Science Foundation of China (NSFC)	International (Regional) Joint Research Programs	U21A20344
National Natural Science Foundation of China (NSFC)		81970452
The Program of Guangdong Provincial Clinical Research		2020B1111170004
The Science and Technology Program of Shenzhen, China		JCYJ20190807161807867
National Natural Science Foundation of China (NSFC)		81870383
The Starting Funding of Faculty from Sun Yat-sen University		2021276
Regional Joint Project for Basic and Applied Basic ResearchFund of Guangdong Province		2022A1515111043
Science and Technology Planning Project of Guangzhou City		2023A04J01601
Guangdong Provincial Key Laboratory of Human DiseaseGenomics		2020B1212070028
Open project of BGl-Shenzhen, Shenzhen, China		BGIRSZ20220008

Submitter

lan ping (lanping@mail.sysu.edu.cn)

Organization

The Sixth Affiliated Hospital, Sun Yat-sen University

Submission date

2024-03-13

Project Data

Resource name	Description