| Accession |
PRJCA024645 |
| Title |
Genome-wide DNA methylation profiling in blood reveals epigenetic signature of incident acute coronary syndrome |
| Relevance |
Medical |
| Data types |
Epigenomics
|
| Organisms |
Homo sapiens
|
| Description |
Baseline blood DNA methylation profiles of 751 incident ACS case-control pairs from the Dongfeng-Tongji (DFTJ) cohort were measured using the Illumina Infinium Methylation EPIC BeadChip. Differentially methylated positions (DMPs) of ACS were identified in the DFTJ samples through conditional logistic regression models with adjustment for smoking status, drinking status, BMI, hypertension, dyslipidemia, diabetes, the proportions of CD8T cell, CD4T cell, natural killer cell, B cells, monocytes, and neutrophils. |
| Sample scope |
Multiisolate |
| Release date |
2024-07-22 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 39198424
|
Genome-wide DNA methylation profiling in blood reveals epigenetic signature of incident acute coronary syndrome
|
Nature Communications
|
10.1038/s41467-024-51751-6
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82021005
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82325044
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82192903
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82192904
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82192900
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82203997
|
|
| Natural Science Fund for Distinguished Young Scholars of Hubei Province
|
|
2022CFA046
|
|
|
|
| Submitter |
Chaolong
Wang (chaolong@hust.edu.cn)
|
| Organization |
Huazhong University of Science and Technology |
| Submission date |
2024-03-25 |
