| Accession |
PRJCA024673 |
| Title |
high-fat diet-induced dysbiosis regulates intestinal lipid metabolism via Ca2+ signaling |
| Relevance |
Medical |
| Data types |
Metabolomics
|
| Organisms |
Drosophila
|
| Description |
In this study, the tyramine-activated enterocyte cytoCa2+ signaling cascade is sufficient to suppress HFD-induced obesity and insulin resistance. Our results suggest that HFD-mediated dysbiosis has a negative feedback effect on gut lipid metabolism via cytoCa2+ signaling. |
| Sample scope |
Monoisolate |
| Release date |
2024-03-26 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 38965418
|
Gut microbiota metabolite tyramine ameliorates high-fat diet-induced insulin resistance via increased Ca(2+) signaling
|
The Embo Journal
|
10.1038/s44318-024-00162-w
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| No funding support
|
|
N/A
|
|
|
|
| Submitter |
peng
ma (1107859346@qq.com)
|
| Organization |
Tongji University |
| Submission date |
2024-03-26 |
