| 项目编号 |
PRJCA024822 |
| 项目标题 |
RNA-Seq of RMn-NBs nanovaccine |
| 涉及领域 |
Medical |
| 数据类型 |
Whole genome sequencing
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
The irradiated tumor itself represents an opportunity to establish endogenous in situ vaccines. However, such in situ cancer vaccination (ISCV) triggered by radiation therapy (RT) alone is very weak and hardly elicits systemic anticancer immunity. In this study, we develop two-dimensional risedronate-manganese nanobelts (RMn-NBs) via coordination-driven self-assembly of Mn2+ and risedronate as a visual in situ cancer nanovaccine to address this issue. We elucidate the specific mechanism of nanovaccines through RNA-seq. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-03-31 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39375342
|
Two-dimensional coordination risedronate-manganese nanobelts as adjuvant for cancer radiotherapy and immunotherapy
|
Nature Communications
|
10.1038/s41467-024-53084-w
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
22275096
|
N/A
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
62288102
|
N/A
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
52002396
|
N/A
|
|
|
| 提交者 |
Zhusheng
Huang (iamzshuang@njupt.edu.cn)
|
| 提交单位 |
Nanjing University of Posts and Telecommunications |
| 提交日期 |
2024-03-31 |
