| Accession |
PRJCA024931 |
| Title |
Rotenone-Induced PINK1/Parkin-mediated Mitophagy |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
Bombyx mori
|
| Description |
We performed transcriptome sequencing of BmN cells treated with 1 µg/mL rotenone to explore the toxicological mechanism of rotenone. The results indicated that rotenone reduced the mitochondrial membrane potential, leading to mitophagy. The PTEN induced putative kinase 1 (PINK1)/Parkin pathway may be involved in rotenone-induced mitophagy. |
| Sample scope |
Monoisolate |
| Release date |
2024-04-07 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
32002235
|
|
| National Natural Science Foundation of China (NSFC)
|
|
31602008
|
|
| Jiangsu Province
|
Postgraduate Research & Practice Innovation Program
|
3742
|
|
|
|
| Submitter |
Min
Tang (mt3138@ujs.edu.cn)
|
| Organization |
Jiangsu University |
| Submission date |
2024-04-03 |
