| Accession |
PRJCA024995 |
| Title |
Secondary metabolism and synthetic biology design of the Important plant metabolites |
| Relevance |
Agricultural |
| Data types |
Genome sequencing and assembly
|
| Organisms |
Escherichia coli
Isodon rubescens
|
| Description |
Synthetic biology is a multi-disciplinary field aiming to rewire a biological behavior in a man-made life systems. Based on a reasonal design, gentic parts are orderly assembled to complete a genetic cirtuit for effective production of desired products. In the past decades, many developed technical applications have been applicated in production of plant secondary metabolites, as well as genetic therapy. However, the aforementioned sussesses mainly produced in a microbal chassis, thus there are many problems that need to be solved, and new chassis systems need to be developed. Compared to microorganisms, plant-based cells have unique advantages in terms of accurate protein processing systems, and autotrophically produce diverse precursor by using carbon dioxide through photosynthesis. In this project, the researches focus on the rational design and assemble the genetic circuit for the synthesis of valuable natural product in E.coli and plant-based hosts. In addition, a plant-based biology bioparts database has also been bulited. |
| Sample scope |
Multiisolate |
| Release date |
2024-04-12 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 36518072
|
|
|
|
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Chinese Academy of Sciences (CAS)
|
Strategic Priority Research Program of Chinese Academy of Sciences (CAS)
|
XDB27020000
|
|
|
|
| Submitter |
Xiaowei
Zhang (xiaoweizhang@cemps.ac.cn)
|
| Organization |
CAS Center for Excellence in Molecular Plant Sciences / Institute of Plant Physiology and Ecology |
| Submission date |
2024-04-07 |
