| 项目编号 |
PRJCA025128 |
| 项目标题 |
MPRA experiment for enhancer activity in HepG2 cell line |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
|
| 物种名称 |
Escherichia coli
Homo sapiens
|
| 描述信息 |
To investigate the regulatory rules of enhancers in mammalian cells, we designed DNA sequences and tested their enhancer activity in the HepG2 cell line using MPRA technology. |
| 样品范围 |
Synthetic |
| 发布日期 |
2024-12-24 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39922842
|
Modeling and designing enhancers by introducing and harnessing transcription factor binding units
|
Nature Communications
|
10.1038/s41467-025-56749-2
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
62250007
|
|
| National Natural Science Foundation of China (NSFC)
|
|
62225307
|
|
|
|
| 提交者 |
Xiaowo
Wang (xwwang@tsinghua.edu.cn)
|
| 提交单位 |
Tsinghua University |
| 提交日期 |
2024-04-09 |
