| Accession |
PRJCA025179 |
| Title |
RNA-seq of hnRNPK knockout and WT MuSCs in different stages of cell proliferation |
| Relevance |
Model organism |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Mus musculus
|
| Description |
Skeletal muscle regeneration is determined by muscle satellite cells. In order to further reveal the mechanism of action of hnRNPK in mouse muscle regeneration, we isolated skeletal muscle satellite cells using Hnrnpk pKO mice and induced knockout, further exploring the role of hnRNPKin satellite cell self-renewal and proliferation. Hnrnpk pKO MuSCs were treated with 4-OHT to induced knockout hnRNPK. 24 and 48 hours after the induction of differentiation, RNA was extracted, and RNA-seq libraries were generated. Hnrnpk pKO MuSCs treated with ethanol as control. |
| Sample scope |
Monoisolate |
| Release date |
2024-04-19 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice
|
Genes & Diseases
|
10.1016/j.gendis.2023.06.031
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
31972537
|
|
|
|
| Submitter |
Yongjie
Xu (xyj@xynu.edu.cn)
|
| Organization |
Xinyang Normal University |
| Submission date |
2024-04-11 |
