Accession PRJCA025225
Title Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution
Relevance Medical
Data types Single cell sequencing
Organisms Homo sapiens
Description The recurrence of cutaneous squamous cell carcinoma (cSCC) after surgery is associated with the reprogramming of the tumor microenvironment (TME), and remains a key factor affecting its outcomes. We employed single-cell RNA sequencing (scRNA-seq) to examine the dynamic changes in epithelial cells, T cells, myeloid cells, and fibroblasts cells between primary and recurrent cSCC.
Sample scope Single cell
Release date 2024-04-12
Publication
PubMed ID Article title Journal name DOI Year
36438481 10.7150/thno.77528
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 81874138
National Natural Science Foundation of China (NSFC) General Program 82073020
National Natural Science Foundation of China (NSFC) National Science Funds for Distinguished Young Scholars 2021JJ10073
China National Postdoctoral Program Innovative Talents BX20220352
China Postdoctoral Science Foundation 2022M713523
Submitter Mingzhu Yin (yinmingzhu2008@126.com)
Organization Chongqing University Three Gorges Hospital
Submission date 2024-04-12

Project Data

Resource name Description