Accession PRJCA025415
Title Accurate estimation of SNP genotypes and genetic relatedness from DNA methylation data
Relevance Medical
Data types Epigenomics
Phenotype or Genotype
Organisms Homo sapiens
Description We propose MethylGenotyper, a method that for the first time enables accurate genotyping at thousands of SNPs directly from commercial DNA methylation microarrays. We used Infinium EPIC array data of 4,662 Chinese in the Dongfeng-Tongji (DFTJ) cohort to test the performance of MethylGenotyper.
Sample scope Multiisolate
Release date 2024-06-04
Publication
PubMed ID Article title Journal name DOI Year
MethylGenotyper: Accurate Estimation of SNP Genotypes and Genetic Relatedness from DNA Methylation Data Genomics, Proteomics & Bioinformatics 10.1093/gpbjnl/qzae044 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 82325044
National Natural Science Foundation of China (NSFC) 82021005
China Postdoctoral Science Foundation 2021M701318
Natural Science Fund for Distinguished Young Scholars of Hubei Province 2022CFA046
Fundamental Research Funds for the Central Universities 2019kfyXJJS036
Fundamental Research Funds for the Central Universities 2023BR030
Submitter Chaolong Wang (chaolong@hust.edu.cn)
Organization Huazhong University of Science and Technology
Submission date 2024-04-19

Project Data

Resource name Description