Description |
Neonatal hyperbilirubinemia, a common clinical condition, is closely associated with immature hepatic function and increased enterohepatic circulation of bilirubin in neonates. Recent studies suggested that gut microbiota may impact neonatal hyperbilirubinemia development, with bifidobacteria showing promise in alleviating symptoms when used adjunctively with conventional treatments like phototherapy. However, uncertainties remain regarding gut bifidobacterial species composition in neonatal hyperbilirubinemia, as well as their effects on bilirubin metabolism and related mechanisms, necessitating further investigation. |