Accession PRJCA025711
Title Modulating the Microbiota-Gut-Liver Axis with Bifidobacterium Species Associated with Breastfeeding to Mitigate Neonatal Hyperbilirubinemia via α-Linolenic Acid and Linoleic Acid Metabolic Pathways
Relevance Agricultural
Data types Non targeted metabolome
Organisms Homo sapiens
Description Neonatal hyperbilirubinemia, a common clinical condition, is closely associated with immature hepatic function and increased enterohepatic circulation of bilirubin in neonates. Recent studies suggested that gut microbiota may impact neonatal hyperbilirubinemia development, with bifidobacteria showing promise in alleviating symptoms when used adjunctively with conventional treatments like phototherapy. However, uncertainties remain regarding gut bifidobacterial species composition in neonatal hyperbilirubinemia, as well as their effects on bilirubin metabolism and related mechanisms, necessitating further investigation.
Sample scope Multiisolate
Release date 2024-04-30
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 32394051 National Natural Science Foundation of China
Submitter chunxiu lin (7200112017@stu.jiangnan.edu.cn)
Organization Jiangnan University
Submission date 2024-04-28

Project Data

Resource name Description