| Accession |
PRJCA026098 |
| Title |
Identification of ferroptosis-related gene signature for tuberculosis diagnosis and therapy efficacy |
| Relevance |
Medical |
| Data types |
Single cell sequencing
|
| Organisms |
Homo sapiens
|
| Description |
Diagnosis of tuberculosis remains a challenge when microbiological tests are negative. Immune cell atlas of patients with active TB and healthy controls were established by single-cell transcriptome. Through integrated analysis of scRNA-seq data with microarray and bulk RNA sequencing data, a ferroptosis-related gene signature were associated with tuberculosis disease was identified. Three gene expression datasets from blood samples of patients with tuberculosis, latent tuberculosis infection and healthy controls were used to assess the diagnostic value of the gene signature. |
| Sample scope |
Single cell |
| Release date |
2024-07-01 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
Identification of ferroptosis-related gene signature for tuberculosis diagnosis and therapy efficacy
|
iScience
|
10.1016/j.isci.2024.110182
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82072233
|
|
|
|
| Submitter |
Bingfen
Yang (yangbingfen@sina.com)
|
| Organization |
the Eighth Medical Center of PLA General Hospital |
| Submission date |
2024-05-13 |
