Accession PRJCA026202
Title Molecular analysis of the T-cell antigen receptor (TCR) repertoire by eliglustat
Relevance Medical
Data types TCRbeta repertoire analysis
Organisms Homo sapiens
Mus
Description To determine whether T-cell expansion involves the exposure of other antigens in addition to the OVA antigen.
Sample scope Multiisolate
Release date 2024-08-06
Publication
PubMed ID Article title Journal name DOI Year
39138212 Inhibition of glycosphingolipid synthesis with eliglustat in combination with immune checkpoint inhibitors in advanced cancers: preclinical evidence and phase I … Nature Communications 10.1038/s41467-024-51495-3 2024
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 8215000340 Triggering mechanism of specific antitumor immune response by targeting glycosphingolipid synthesis in tumor cells and clinical study
Submitter Weidong Han (hanwdrsw@163.com)
Organization the First Medical Center, Chinese PLA General Hospital
Submission date 2024-05-16

Project Data

Resource name Description
BioSample (54)  show -
GSA (1) -
CRA018126 TCRbeta repertoire analysis from tumour-infiltrating lymphocytes (MC38)