| Accession |
PRJCA026998 |
| Title |
De novo generation of macrophage from placenta-derived hemogenic endothelium |
| Relevance |
Model organism |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| Organisms |
Mus musculus
|
| Description |
We profile the transcriptional landscape of mouse fetal placenta and identify four distinct types of haematopoietic stem/progenitor cells (HSPCs) during mid-gestation using single-cell RNA sequencing. We experimentally validate and uncover that a subpopulation of placental endothelial cells exhibits hemogenic endothelial (HE) potential and shares transcriptional features with HE cells in the aorta-gonad-mesonephros (AGM) region. |
| Sample scope |
Single cell |
| Release date |
2024-08-31 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 34197725
|
|
|
|
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2018YFA0800200
|
|
|
|
| Submitter |
yongjie
Li (liyongjie23@mails.ucas.ac.cn)
|
| Organization |
Institute of Zoology, Chinese Academy of Sciences |
| Submission date |
2024-06-13 |
