Accession | PRJCA027034 | ||||||||||
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Title | Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity | ||||||||||
Relevance | Model organism | ||||||||||
Data types |
Epigenomics
Transcriptome or Gene expression Raw sequence reads Single cell sequencing |
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Organisms | Danio rerio | ||||||||||
Description | Using a combination of single-cell multi-omics, lineage tracing and functional assays, we show that embryonic HSPCs are originated from heterogeneous hemogenic endothelial cells (HECs) during zebrafish embryogenesis. | ||||||||||
Sample scope | Single cell | ||||||||||
Release date | 2024-08-31 | ||||||||||
Publication |
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Grants |
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Submitter | yongjie Li (liyongjie23@mails.ucas.ac.cn) | ||||||||||
Organization | Institute of Zoology, Chinese Academy of Sciences | ||||||||||
Submission date | 2024-06-14 |