Accession PRJCA027034
Title Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity
Relevance Model organism
Data types Epigenomics
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
Organisms Danio rerio
Description Using a combination of single-cell multi-omics, lineage tracing and functional assays, we show that embryonic HSPCs are originated from heterogeneous hemogenic endothelial cells (HECs) during zebrafish embryogenesis.
Sample scope Single cell
Release date 2024-08-31
Publication
PubMed ID Article title Journal name DOI Year
37016019
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2018YFA0800200
Submitter yongjie Li (liyongjie23@mails.ucas.ac.cn)
Organization Institute of Zoology, Chinese Academy of Sciences
Submission date 2024-06-14

Project Data

Resource name Description
BioSample (19)  show -
GSA (1) -
CRA017058 Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity