| Accession |
PRJCA027384 |
| Title |
A genome-wide expression profiling data of 81 rectal cancer patients with neoadjuvant chemoradiotherapy |
| Relevance |
Medical |
| Data types |
Whole Human Genome Microarrays
|
| Organisms |
Homo sapiens
|
| Description |
To explore whether gene expression profiles of primary rectal carcinomas could offer a specific gene signature that determine response to preoperative chemoradiotherapy, we conducted a study with eighty-one individuals with locally advanced rectal carcinomas to establish a molecular signature for response classification based on genome-wide mRNA expression analysis. Class-comparison statistics between good response patients (Tumor Regression Grade 1 and 2) and poor response patients (Tumor Regression Grade 4 and 5) were used to correlate the expression results with tumor regression grade after preoperative chemoradiotherapy. |
| Sample scope |
Monoisolate |
| Release date |
2024-06-25 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 39571490
|
ZNF37A downregulation promotes TNFRSF6B expression and leads to therapeutic resistance to concurrent chemoradiotherapy in rectal cancer patients
|
Translational Oncology
|
10.1016/j.tranon.2024.102203
|
2024
|
| 40200809
|
MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer
|
Cancer Biology & Medicine
|
10.20892/j.issn.2095-3941.2024.0540
|
2025
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81972859
|
|
|
|
| Submitter |
ningxin
Ren (renningxin01@163.com)
|
| Organization |
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital |
| Submission date |
2024-06-25 |
