| 项目编号 |
PRJCA027384 |
| 项目标题 |
A genome-wide expression profiling data of 81 rectal cancer patients with neoadjuvant chemoradiotherapy |
| 涉及领域 |
Medical |
| 数据类型 |
Whole Human Genome Microarrays
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
To explore whether gene expression profiles of primary rectal carcinomas could offer a specific gene signature that determine response to preoperative chemoradiotherapy, we conducted a study with eighty-one individuals with locally advanced rectal carcinomas to establish a molecular signature for response classification based on genome-wide mRNA expression analysis. Class-comparison statistics between good response patients (Tumor Regression Grade 1 and 2) and poor response patients (Tumor Regression Grade 4 and 5) were used to correlate the expression results with tumor regression grade after preoperative chemoradiotherapy. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-06-25 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39571490
|
ZNF37A downregulation promotes TNFRSF6B expression and leads to therapeutic resistance to concurrent chemoradiotherapy in rectal cancer patients
|
Translational Oncology
|
10.1016/j.tranon.2024.102203
|
2024
|
| 40200809
|
MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer
|
Cancer Biology & Medicine
|
10.20892/j.issn.2095-3941.2024.0540
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
81972859
|
|
|
|
| 提交者 |
ningxin
Ren (renningxin01@163.com)
|
| 提交单位 |
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital |
| 提交日期 |
2024-06-25 |
