Accession PRJCA027384
Title A genome-wide expression profiling data of 81 rectal cancer patients with neoadjuvant chemoradiotherapy
Relevance Medical
Data types Whole Human Genome Microarrays
Organisms Homo sapiens
Description To explore whether gene expression profiles of primary rectal carcinomas could offer a specific gene signature that determine response to preoperative chemoradiotherapy, we conducted a study with eighty-one individuals with locally advanced rectal carcinomas to establish a molecular signature for response classification based on genome-wide mRNA expression analysis. Class-comparison statistics between good response patients (Tumor Regression Grade 1 and 2) and poor response patients (Tumor Regression Grade 4 and 5) were used to correlate the expression results with tumor regression grade after preoperative chemoradiotherapy.
Sample scope Monoisolate
Release date 2024-06-25
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81972859
Submitter ningxin Ren (renningxin01@163.com)
Organization National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital
Submission date 2024-06-25

Project Data

Resource name Description