Accession

PRJCA027550

Title

Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell anti-tumor immunity

Relevance

Medical

Data types

Transcriptome or Gene expression
Single cell sequencing

Organisms

Mus musculus
Homo sapiens

Description

Discovery of small molecules which induce MHC-I up-regulation and improve the efficacy of T-cell-based immunotherapy.

Sample scope

Multispecies

Release date

2024-06-30

Grants

Agency	program	Grant ID	Grant title
National Natural Science Foundation of China (NSFC)		82073413
National Natural Science Foundation of China (NSFC)		22137002
National Natural Science Foundation of China (NSFC)		21877016
National Natural Science Foundation of China (NSFC)		92253305
National Natural Science Foundation of China (NSFC)		82273021
National Natural Science Foundation of China (NSFC)		81972621

Submitter

Qian Yu (1016531759@qq.com)

Organization

Fudan University

Submission date

2024-06-30

Project Data

Resource name	Description
BioSample (8) show	-
SAMC3989838	SU-DHL-4 cells treated
SAMC3989837	SU-DHL-4 cells treated
SAMC3989836	SU-DHL-4 cells
SAMC3989835	SU-DHL-4 cells
SAMC3964079	Single-cell RNA-seq of mus musculus: B16F10 melanoma tumor tissue treated with bleomycin
SAMC3964078	Single-cell RNA-seq of mus musculus: B16F10 melanoma tumor tissue
SAMC3955308	Single-cell RNA-seq of mus musculus: B16F10 melanoma tumor tissue treated with bleomycin
SAMC3955307	Single-cell RNA-seq of mus musculus: B16F10 melanoma tumor tissue
GSA (1)	-
CRA017507	Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell anti-tumor immunity