| 项目编号 |
PRJCA027862 |
| 项目标题 |
The Role of Myeloid Cells in the Pathogenesis of Biliary Atresia |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
|
| 描述信息 |
This study elucidates the role of LOX-1+ PMN-MDSCs in BA pathogenesis and assesses their potential as non-invasive early diagnostic biomarkers. We analyzed the expression and activity of these cells in peripheral blood from BA patients and controls. Transcriptional analysis of whole blood CD15+LOX-1+ PMN-MDSC from control and BA patients was conducted using Smart-seq2. Our findings reveal a significant increase in the frequencies and function of LOX-1+ PMN-MDSCs in BA patients. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2026-04-24 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
U23A20409
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82001691
|
|
| Science and Technology Planning Project of Guangzhou
|
|
202206080002
|
|
| Science and Technology Planning Project of Guangzhou
|
|
2023B03J1299
|
|
| Science and Technology Planning Project of Guangzhou
|
|
2024A03J1237
|
|
| Guangzhou Medical University Scientific Research Ability Improvement Project
|
|
2302155XM
|
|
|
|
| 提交者 |
Juan
He (2014689001@gzhmu.edu.cn)
|
| 提交单位 |
Guangzhou Women and Children's Medical Center |
| 提交日期 |
2024-07-09 |
