| 项目编号 |
PRJCA028154 |
| 项目标题 |
Base editing efficiency of 5NABE at six different genomic loci in HEK293T cells using higher fluorescence thresholds |
| 涉及领域 |
Medical |
| 数据类型 |
Targeted Locus (Loci)
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Cells with higher fluorescence threshold were flow sorted, the genome was extracted to amplify fragments containing target sequences, and editing efficiencies were analysed using CRISPResso2 after NGS sequencing. |
| 样品范围 |
Synthetic |
| 发布日期 |
2024-07-16 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39179566
|
Engineered minimal type I CRISPR-Cas system for transcriptional activation and base editing in human cells
|
Nature Communications
|
10.1038/s41467-024-51695-x
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Chinese Academy of Sciences (CAS)
|
Strategic Priority Research Program of Chinese Academy of Sciences (CAS)
|
XDA24020101
|
|
|
|
| 提交者 |
Hua
Xiang (xiangh@im.ac.cn)
|
| 提交单位 |
Institute of Microbiology, Chinese Academy of Sciences |
| 提交日期 |
2024-07-16 |
