| 项目编号 |
PRJCA028161 |
| 项目标题 |
Senolytics reduce senescent characteristics and enhance activation of tumor-infiltrating CD4+ Naive T cells |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
To investigate the unique functionality of significantly increased CD4+CD62L+ Naive T cells in tumors after combined anti-PD-1+DQ therapy in anti-tumor immunity, we isolated CD62L+CD44-CD4+ cells from tumors of mice treated with Isotype, anti-PD-1, or anti-PD-1+DQ, and performed RNA-Seq and ATAC-Seq. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-04-24 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Sun Yat-sen University
|
the Fundamental Research Funds for the Central Universities
|
16ykpy10
|
|
| Sun Yat-sen University
|
the Fundamental Research Funds for the Central Universities
|
19ykzd20
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82373452
|
|
| National Natural Science Foundation of China (NSFC)
|
The Joint Funds
|
U21A20381
|
|
| Guangdong Basic and Applied Basic Research Foundation
|
|
2021A1515220138
|
|
| Guangdong Natural Science Funds for Distinguished Young Scholar
|
|
2022B1515020061
|
|
|
|
| 提交者 |
Song
Fan (fansong2@mail.sysu.edu.cn)
|
| 提交单位 |
Sun Yat-sen Memorial Hospital, Sun Yat-sen University |
| 提交日期 |
2024-07-16 |
