| Accession |
PRJCA028383 |
| Title |
Spatial multi-omics uncovering tumor structures and cell type specific metabolites in primary and microvascular invasion HCC |
| Relevance |
Medical |
| Data types |
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
In this study, we collected the tumor boundary tissues of MVI+ and MVI- patients, along with distant paratumor tissues, and performed spatial transcriptome and metabolism sequencing. By comparing gene expression and metabolite signal intensities between MVI+ and MVI- tissues, we observed significant alterations in lipid metabolism activities within tumor and peritumoral regions during HCC progression from MVI- to MVI+. |
| Sample scope |
Multiisolate |
| Release date |
2024-08-01 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
No.12375349
|
|
| National Natural Science Foundation of China (NSFC)
|
|
No.12175167
|
|
| Innovation Group of Hubei Provincial Natural Science Foundation
|
|
No.2022CFA005
|
|
|
|
| Submitter |
Fubing
Wang (wangfubing@znhospital.cn)
|
| Organization |
Zhongnan Hospital of Wuhan University |
| Submission date |
2024-07-22 |
