| 项目编号 |
PRJCA028383 |
| 项目标题 |
Spatial multi-omics uncovering tumor structures and cell type specific metabolites in primary and microvascular invasion HCC |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
In this study, we collected the tumor boundary tissues of MVI+ and MVI- patients, along with distant paratumor tissues, and performed spatial transcriptome and metabolism sequencing. By comparing gene expression and metabolite signal intensities between MVI+ and MVI- tissues, we observed significant alterations in lipid metabolism activities within tumor and peritumoral regions during HCC progression from MVI- to MVI+. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2024-08-01 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
No.12375349
|
|
| National Natural Science Foundation of China (NSFC)
|
|
No.12175167
|
|
| Innovation Group of Hubei Provincial Natural Science Foundation
|
|
No.2022CFA005
|
|
|
|
| 提交者 |
Fubing
Wang (wangfubing@znhospital.cn)
|
| 提交单位 |
Zhongnan Hospital of Wuhan University |
| 提交日期 |
2024-07-22 |
