| Accession |
PRJCA028691 |
| Title |
The molecular mechanisms of dynamic regulation of chromatin structure and function |
| Relevance |
Model organism |
| Data types |
Transcriptome or Gene expression
image data
|
| Organisms |
Mus musculus
Homo sapiens
|
| Description |
This project focuses on the scientific issue of the role of epigenetic imbalance in the development and progression of major diseases. It aims to explore the molecular mechanisms underlying the establishment, maintenance, and regulation of higher-order chromatin structure, and to reveal their relationship with the occurrence and progression of related diseases. The goal is to provide new strategies for the diagnosis and treatment of these diseases. |
| Sample scope |
Monoisolate |
| Release date |
2024-08-01 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
H2A mono-ubiquitination differentiates FACT's functions in nucleosome assembly and disassembly
|
Nucleic Acids Res .
|
10.1093/nar/gkab1271
|
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2018YFE0203300
|
|
|
|
| Submitter |
Cuifang
Liu (lcuifang@126.com)
|
| Organization |
Institute of Biophysics, Chinese Academy of Sciences |
| Submission date |
2024-07-31 |
