| 项目编号 |
PRJCA028777 |
| 项目标题 |
Single cell transcriptome profiling of immune tissues from germ free and specific pathogen free piglets |
| 涉及领域 |
Agricultural |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Sus scrofa
|
| 描述信息 |
The commensal microbiota colonizes various tissues of the body, which is crucial for host metabolism, growth, development, and immunity. However, the research on microbial host immunity is not only lacking in large animal models, but the effects of commensal microbiota on immune tissues are limited at the molecular level. This is partially attributed to the lack of monitoring tools for tracking alterations within cell clusters in immune tissues associated with commensal microbiota. Here, we utilized single cell RNA sequencing to analyze containing 6 samples from germ free and specific pathogen free piglets Peyer patches PPs, mesenteric lymph nodes, and spleen, and the changes of immune cells after commensal microbiota colonization were investigated. |
| 样品范围 |
Single cell |
| 发布日期 |
2025-01-04 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40251240
|
Single cell transcriptome profiling of immune tissues from germ-free and specific pathogen-free piglet
|
Scientific Data
|
10.1038/s41597-025-04957-2
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
32072687
|
|
| National Natural Science Foundation of China (NSFC)
|
|
32302712
|
|
|
|
| 提交者 |
jinwei
zhang (jinweizhang50@163.com)
|
| 提交单位 |
Chongqing Academy of Animal Sciences |
| 提交日期 |
2024-08-02 |
