| 项目编号 |
PRJCA028904 |
| 项目标题 |
Hyper-Oxygenating Respiratoid Biosystem for Therapeutic Cell Transplantation |
| 涉及领域 |
Medical |
| 数据类型 |
Whole genome sequencing
|
| 物种名称 |
Spinacia oleracea
|
| 描述信息 |
The study introduces an innovative respiratoid biosystem that addresses the critical issue of oxygen supply to transplanted cells by leveraging chloroplast-transit-peptide (CTP). By conjugating CTP with alginate, the system stabilizes chloroplast structures, ensuring their integrity and enhancing the expression of photosynthesis-associated genes. This leads to efficient oxygen generation, particularly under hypoxic conditions (~1% pO2). The biosystem's ability to spontaneously produce oxygen makes it a valuable tool for cell transplantation and tissue engineering, where maintaining adequate oxygen levels is essential for cell survival and function. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-08-07 |
| 出版信息 |
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Research Foundation of Korea (NRF)
|
|
NRF-2020R1A2C3005834
|
|
| National Research Foundation of Korea (NRF)
|
|
NRF-2022R1A4A1030421
|
|
| Korean Fund for Regenerative Medicine (KFRM)
|
|
KFRM24A0105L1
|
|
|
|
| 提交者 |
Chaerim
Yoo (chaerimu@gmail.com)
|
| 提交单位 |
Hanyang University |
| 提交日期 |
2024-08-07 |
