| 项目编号 |
PRJCA028950 |
| 项目标题 |
Celastrol reduces cisplatin-induced nephrotoxicity in kidney organoids derived from human iPSCs |
| 涉及领域 |
Cell Biolology |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Celastrol, an active ingredient derived from Tripterygium wilfordii Hook F, has shown therapeutic potential for various kidney renal diseases. However, its dose-dependent toxicity and protective effects against kidney damage require further investigation. This study aimed to develop a kidney organoid-based prediction system to assess the safety and efficacy of celastrol in reducing cisplatin-induced nephrotoxicity. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-08-08 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82174226
|
|
|
|
| 提交者 |
Qizheng
Wang (wang_qizheng@gibh.ac.cn)
|
| 提交单位 |
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences |
| 提交日期 |
2024-08-06 |
