Accession PRJCA029113
Title Major Depressive Disorder Response to Antidepressant Treatment
Relevance Medical
Data types Epigenomics
Transcriptome or Gene expression
Organisms Homo sapiens
Description The mechanism involved in major depressive disorder (MDD) is well-studied but the mechanistic origin of the heterogeneous antidepressant effect remains largely unknown. Single-cell RNA-sequencing (scRNA-seq) and assay for transposase-accessible chromatin using sequencing (ATAC-seq) on peripheral blood mononuclear cells from 8 healthy individuals and 8 MDD patients before or after 12 weeks of antidepressant treatment is performed.
Sample scope Single cell
Release date 2024-08-14
Publication
PubMed ID Article title Journal name DOI Year
38867657
Data provider
Data provider Data provider URL
Capital Medical University https://www.ccmu.edu.cn/
Biomaterial provider Advanced Innovation Center for Human Brain Protection
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 82171526
National Natural Science Foundation of China (NSFC) General Program 82171525
Submitter Bowen Zhang (zhangbw@bnu.edu.cn)
Organization Beijing Normal University
Submission date 2024-08-14

Project Data

Resource name Description