Accession PRJCA029538
Title Single-cell RNA sequencing analysis reveals tumor microenvironment in murine mammary EO771 tumors
Relevance Medical
Data types Single cell sequencing
Organisms Mus musculus
Homo sapiens
Description To investigate the impact of IGF2 in the tumor microenvironment, we obtained EO771 tumors from wild-type (WT) and IGF2 conditional knockout (cKO) mice and performed single-cell RNA sequencing (scRNA-seq) analysis.
Sample scope Single cell
Release date 2024-10-08
Publication
PubMed ID Article title Journal name DOI Year
39545420 Insulin-like growth factor 2 drives fibroblast-mediated tumor immunoevasion and confers resistance to immunotherapy The Journal of Clinical Investigation 10.1172/JCI183366 2024
39602462 Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy Cancer Immunology Research 10.1158/2326-6066.CIR-24-0484 2025
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 82372886
Submitter Hongzhong Li (lihongzhong@cqmu.edu.cn)
Organization The First Affiliated Hospital of Chongqing Medical University
Submission date 2024-08-27

Project Data

Resource name Description
BioSample (12)  show -
GSA (1) -
CRA018666 scRNA-seq of EO771 tumors