| 项目编号 | PRJCA029786 | ||||||||||||||||||||||||||||
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| 项目标题 | Gut mucosal mycobiome-centric multiomics profiling in Crohn's disease uncovers Cladosporium sphaerospermum countering inflammation via AMP | ||||||||||||||||||||||||||||
| 涉及领域 | Medical | ||||||||||||||||||||||||||||
| 数据类型 |
Whole genome sequencing
Metagenome Transcriptome or Gene expression Genome sequencing and assembly Raw sequence reads Genome sequencing |
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| 物种名称 |
Mus musculus
Homo sapiens human gut metagenome |
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| 描述信息 | Crohn's disease (CD) is a subtype of inflammatory bowel disease primarily inflicting the terminal ileum, and gut microbiome abnormality is aetiological. However, the small bowel mucosa-associated fungi and their metabolic functions, particularly for the protective ones, were largely unexplored. Here, we enrolled CD patients and healthy individuals from 3 independent cohorts and conducted multi-omics profiling of the ileal mucosal mycobiome and bacteriome, and the fecal mycobiome, bacteriome, and metabolome. | ||||||||||||||||||||||||||||
| 样品范围 | Multispecies | ||||||||||||||||||||||||||||
| 发布日期 | 2025-10-30 | ||||||||||||||||||||||||||||
| 项目资金来源 |
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| 提交者 | Tao Zuo (zuot@mail.sysu.edu.cn) | ||||||||||||||||||||||||||||
| 提交单位 | The Sixth Affiliated Hospital, Sun Yat-sen University | ||||||||||||||||||||||||||||
| 提交日期 | 2024-09-03 |
| 资源名称 | 描述 |
|---|---|
| BioSample (909) show | - |
| GSA (2) | - |
| CRA026420 | Gut mucosal mycobiome-centric multiomics profiling in Crohn's disease uncovers Cladosporium sphaerospermum countering inflammation via AMP (microbiota) |
| CRA018913 | Gut mucosal mycobiome-centric multiomics profiling in Crohn's disease uncovers Cladosporium sphaerospermum countering inflammation via AMP (animal experiment) |