| Accession |
PRJCA029933 |
| Title |
TMT-MS analysis of MED-B-4 treated MiaPaCa2 cells |
| Relevance |
Medical |
| Data types |
Proteomic data
|
| Organisms |
Homo sapiens
|
| Description |
MED-B-4, a Sappanone A derivative compound, is designed as IMPDH2 selective PROTAC degrader. MiaPaCa2 is a pancreatic ductal cancer cell line which expresses IMPDH2 as an essential gene. MiaPaCa2 cells were treated with MED-B-4 at 2.5uM and 5uM respectively for 8 hours before subjected to Tandem Mass Tag (TMT) System based mass spectrum analysis for differently expressed proteins. |
| Sample scope |
Monoisolate |
| Release date |
2024-09-06 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
82203434
|
|
|
|
| Submitter |
Di
Wu (diwu09@fudan.edu.cn)
|
| Organization |
Fudan University |
| Submission date |
2024-09-06 |
