| 项目编号 |
PRJCA030245 |
| 项目标题 |
Cortical arealization of interneurons in developing human and macaque brains |
| 涉及领域 |
Evolution |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
Single cell sequencing
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
Cortical interneurons generated from ganglionic eminence via a long-distance journey of tangential migration display evident cellular and molecular differences across brain regions, which seeds the heterogeneous cortical circuitry in primates. However, whether such regional specifications in interneurons are intrinsically encoded or gained through interactions with the local milieu remains elusive. Here, we recruit over 700,000 interneurons from cerebral cortex and subcortex including ganglionic eminence within the developing human and macaque species. The spatial and temporal characteristics of cortical interneurons are described through analysis, providing a new proxy for understanding the relationship between cell diversity and functional progression. |
| 样品范围 |
Single cell |
| 发布日期 |
2024-11-29 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
32270715
|
|
|
|
| 提交者 |
Mingfeng
Li (mingfengli@hust.edu.cn)
|
| 提交单位 |
Huazhong University of Science and Technology |
| 提交日期 |
2024-09-17 |
