| 项目编号 |
PRJCA030614 |
| 项目标题 |
Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Single cell sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Background: Exercise rehabilitation therapy, particularly resistance exercise, has garnered widespread recognition for its beneficial effects on the restoration of locomotor function in individuals with spinal cord injury (SCI). Notably, resistance exercise has demonstrated significant improvements in muscle strength, coordination, and overall functional recovery. However, to optimize clinical management and mimic exercise-like effects, it is imperative to obtain a comprehensive understanding of the molecular alterations that underlie these positive effects. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-01-22 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39910614
|
Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury
|
Genome Medicine
|
10.1186/s13073-025-01434-8
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Shanghai Municipal Health Commission
|
|
2022XD050
|
|
| Shanghai Municipal Education Commission
|
|
22SG12
|
|
| Shanghai YangZhi Rehabilitation Hospital
|
|
2022GGRC06
|
|
| Shanghai YangZhi Rehabilitation Hospital
|
|
KYPY202009
|
|
| China Disabled Person Federation
|
|
2023CDPFAT-30
|
|
| the National Key R&D Program of China
|
|
2023YFC2508900
|
|
| Shanghai Hospital Development Center Foundation-Shanghai Municipal Hospital Rehabilitation Medicine Specialty Alliance
|
|
SHDC22023304
|
|
|
|
| 提交者 |
Lin
Cheng (lincheng@shsmu.edu.cn)
|
| 提交单位 |
Shanghai Institute of Hematology, Shanghai Jiaotong University School of Medicine |
| 提交日期 |
2024-09-27 |
