Accession PRJCA030731
Title Yangmo Decoction treats intrauterine adhesions by regulating vaginal microbiota
Relevance Microbiology
Data types Metagenome
Organisms vaginal metagenome
Description Intrauterine adhesion (IUA) is one of the common gynecological diseases leading to infertility. Depart from hysteroscopic surgery, oral agents could be advantageous choice in terms of convenience for patients. Compared to Western medicine (WM) such as estrogen, traditional Chinese medicine (TCM) has fewer side effects and is increasingly chosen by women with gynecological disorders. However, the effect of TCM and WM on vaginal microbiota of IUA patients remains to be researched. In this study, a rat model of IUA performed by curettage was established, and respectively treated by estrogen and Yangmo decoction. We compared the differences of vaginal microbial composition in IUA rats and healthy rats and aimed to figure out the effect of Yangmo decoction and estrogen on vaginal microbiota for IUA rats.
Sample scope Multispecies
Release date 2024-09-30
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 32170071
National Natural Science Foundation of China (NSFC) 32300051
Hunan Provincial Natural Science Foundation of China 2024JJ9451
Central South University Innovation-Driven Research Programme 2023CXQD059
Submitter Chunyan Li (fclichunyan@126.com)
Organization Central South University
Submission date 2024-09-30

Project Data

Resource name Description
BioSample (30)  show -
GSA (1) -
CRA019384 Yangmo Decoction treats intrauterine adhesions by regulating vaginal microbiota