| 项目编号 |
PRJCA031086 |
| 项目标题 |
Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome |
| 涉及领域 |
Medical |
| 数据类型 |
metabolome
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
To examine the disparities in serum and intestinal tissue metabolites between a perimenopausal rat model and control rats, and to analyze the diversity and functionality of intestinal microorganisms to determine potential correlation between intestinal flora and metabolites.We established a rat model of perimenopausal syndrome (PMS) and performed an integrated analysis of metabolome and microbiome. The findings of this study are expected to contribute to understanding the indications and contraindications for estrogen application in perimenopausal women and to aid in the development of appropriate therapeutic agents. |
| 样品范围 |
Synthetic |
| 发布日期 |
2024-10-12 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
|
|
Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome
|
mSystems
|
10.1128/msystems.00623-24
|
2024
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Other
|
|
ZR2023MH380
|
Natural Science Foundation of Shandong Province
|
|
|
| 提交者 |
Xiujuan
Cui (drcuixj@163.com)
|
| 提交单位 |
Tengzhou Central People's Hospital |
| 提交日期 |
2024-10-12 |
