| Accession |
PRJCA031086 |
| Title |
Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome |
| Relevance |
Medical |
| Data types |
metabolome
|
| Organisms |
Mus musculus
|
| Description |
To examine the disparities in serum and intestinal tissue metabolites between a perimenopausal rat model and control rats, and to analyze the diversity and functionality of intestinal microorganisms to determine potential correlation between intestinal flora and metabolites.We established a rat model of perimenopausal syndrome (PMS) and performed an integrated analysis of metabolome and microbiome. The findings of this study are expected to contribute to understanding the indications and contraindications for estrogen application in perimenopausal women and to aid in the development of appropriate therapeutic agents. |
| Sample scope |
Synthetic |
| Release date |
2024-10-12 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
|
|
Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome
|
mSystems
|
10.1128/msystems.00623-24
|
2024
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Other
|
|
ZR2023MH380
|
Natural Science Foundation of Shandong Province
|
|
|
| Submitter |
Xiujuan
Cui (drcuixj@163.com)
|
| Organization |
Tengzhou Central People's Hospital |
| Submission date |
2024-10-12 |
