| Accession |
PRJCA031805 |
| Title |
colon cancer and liver metastasizes |
| Relevance |
Medical |
| Data types |
Map
|
| Organisms |
Mus musculus
Homo sapiens
|
| Description |
Here, we demonstrate that CRC-derived exosomes create an immunosuppressive PMN. Exosomes from CT-26 cells, a murine colon carcinoma line, polarize M1 macrophages into the M2 phenotype and reduce CD8+ T cell viability, consequently leading to liver metastasis of CRC. Therefore, we hope to find out which protein in exosome plays an important role in this phenomenon by LC-MS. |
| Sample scope |
Monoisolate |
| Release date |
2024-10-30 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81472705
|
|
|
|
| Submitter |
Li
Jiang (prof_jiang2023@163.com)
|
| Organization |
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| Submission date |
2024-10-30 |
