| Accession |
PRJCA032274 |
| Title |
ACTRT2 deficiency increases spermatogonia vulnerability to ferroptosis |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
Spermatogonia are vulnerable to various external damage factors and would be caused to cell death. However, the mechanism is still unclear. In this study, we aimed to explore the RNA associated with spermatogenic function by comparing their expression in seminal plasma extracellular vesicles. And we found that the actin-related proteins T2, ACTRT2 was specifically expressed in testicular tissue and was associated with spermatogenesis. |
| Sample scope |
Multiisolate |
| Release date |
2024-11-12 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81971759
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82171604
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
82171564
|
|
| Basic and Applied Basic Research Foundation of Guangdong Province
|
|
2021A1515111195
|
|
| Basic and Applied Basic Research Foundation of Guangdong Province
|
|
2023A1515140055
|
|
|
|
| Submitter |
Guihua
Liu (liuguihua@mail.sysu.edu.cn)
|
| Organization |
The Sixth Affiliated Hospital, Sun Yat-sen University |
| Submission date |
2024-11-12 |
