| 项目编号 |
PRJCA032869 |
| 项目标题 |
Enhanced Myofibroblast Differentiation of eMSCs in Intrauterine Adhesions |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Intrauterine adhesions (IUA) is one of the most common gynecological diseases and main causes of uterine infertility. Among proposed hypotheses on IUA development, the reduced endometrial regeneration resulting from loss of functional stem cells has been proposed as the key factor affecting the IUA prognosis. However, the underlying mechanisms mostly remain unclear. Because the eMSCs (endometrial mesenchymal stem/stromal cells) play a critical role in both supporting the gland development and also preparing the environment for embryo implantation through decidualization, the characteristics and functions were compared between the eMSCs derived from IUA and non-IUA patients, to uncover the important roles of eMSCs in IUA and also the underlying mechanisms. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-11-27 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 39901307
|
Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions
|
Stem Cell Research & Therapy
|
10.1186/s13287-025-04183-y
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Guangdong Basic and Applied Basic Research Foundation
|
|
2023A1515010181
|
|
|
|
| 提交者 |
Jianyong
Xu (xujianyong820915@163.com)
|
| 提交单位 |
Shenzhen Zhongshan Urology Hospital |
| 提交日期 |
2024-11-27 |
