| 项目编号 |
PRJCA033574 |
| 项目标题 |
metabolomic of congenital hepatic fibrosis mice |
| 涉及领域 |
Model organism |
| 数据类型 |
Metabonomics
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
Congenital hepatic fibrosis (CHF) caused by mutations in the polycystic kidney and hepatic disease 1 (PKHD1) gene is a rare genetic disorder with poorly understood pathogenesis. We hypothesized that integrating gut microbiome and metabolomic analyses could uncover distinct host-microbiome interactions in CHF mice compared to wild-type controls. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-03-08 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40165060
|
Multi-omics analysis of host-microbiome interactions in a mouse model of congenital hepatic fibrosis
|
BMC Microbiology
|
10.1186/s12866-025-03892-x
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
No.82472167
|
|
|
|
| 提交者 |
mengfan
jiao (jiaomengfan2019@163.com)
|
| 提交单位 |
The First Affiliated Hospital with Nanjing Medical University |
| 提交日期 |
2024-12-12 |
