| 项目编号 |
PRJCA033924 |
| 项目标题 |
Exploring the heterogeneity of PBMC in advanced NSCLC based on single-cell transcriptome sequencing technology |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Single cell sequencing
|
| 物种名称 |
|
| 描述信息 |
Peripheral blood mononuclear cells (PBMCs) encompass a variety of immune cell types, which, along with their associated molecular signatures, can serve as potential biomarkers for oncological diseases. Nonetheless, current literature has not thoroughly characterized the heterogeneous nature of peripheral blood immune cell populations in the context of lung cancer. Our investigation aims to delineate the distinct compositional profiles and transcriptomic variations between advanced lung cancer (A1, A2, A3) and normal human (A4) peripheral blood immune cells at a single-cell resolution, utilizing advanced single-cell transcriptome sequencing techniques. Furthermore, this study seeks to uncover the unique regulatory mechanisms governing gene expression in lung cancer, ultimately contributing to the identification of novel biomarkers for its diagnosis. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2026-01-31 |
| 实验材料提供者 |
Biomarker Technologies of Beijing, China |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Science and Technology Department of Ningxia
|
Key R&D plans
|
2023BEG02002
|
Clinical application research on monitoring recurrence and metastasis of lung cancer and precise individualized diagnosis and treatment using acoustic microfluidic technology
|
|
|
| 提交者 |
Zhijun
Zhao (z15815z@163.com)
|
| 提交单位 |
General Hospital of Ningxia Medical University |
| 提交日期 |
2024-12-19 |
