| 项目编号 |
PRJCA034289 |
| 项目标题 |
Tumor Suppressor RASAL1 Inactivation via Aberrant Splicing |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
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| 描述信息 |
RAS GTPase-activating-like protein 1 (RASAL1) is a prominent tumor suppressor, whose loss is a well-established robust oncogenic mechanism. The RASAL1 variants displayed different patterns of regulation at the protein synthesis level. To explore the underlying mechanism, this study investigates the variant-specific translation patterns of RASAL1 (RASAL1-001 and RASAL1-004) in the WRO cell line using a combination of ribosome profiling and RNA sequencing analyses. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2024-12-30 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| No funding support
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| 提交者 |
Mingzhao
Xing (xingmz@sustech.edu.cn)
|
| 提交单位 |
Southern University of Science and Technology |
| 提交日期 |
2024-12-28 |
