| Accession |
PRJCA034312 |
| Title |
Single-cell delineation of the microbiota-gut-brain axis: probiotic intervention in Chd8 haploinsufficient mice |
| Relevance |
Model organism |
| Data types |
Raw sequence reads
|
| Organisms |
Mus musculus
|
| Description |
we employed chromodomain helicase DNA-binding protein 8 (CHD8)-haploinsufficient model for autism spectrum disorder (ASD) to dissect the interaction pathways between the host and gut microbiota. We built a comprehensive single-cell transcriptome atlas of the brain and intestinal tissues of wild-type and mutant mice, spanning three critical developmental periods. |
| Sample scope |
Single cell |
| Release date |
2024-12-29 |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
32025009
|
|
| National Natural Science Foundation of China (NSFC)
|
|
91951209
|
|
| National Natural Science Foundation of China (NSFC)
|
|
31722031
|
|
| National Natural Science Foundation of China (NSFC)
|
|
32470714
|
|
|
|
| Submitter |
Peifeng
Ji (jipeifeng@biols.ac.cn)
|
| Organization |
Beijing Institutes of Life Science, Chinese Academy of Sciences |
| Submission date |
2024-12-29 |
