| 项目编号 |
PRJCA034579 |
| 项目标题 |
Expression profiling of HT29 and U87-MG cells after treatment with ZYH005, a synthesized phenanthridinone-based alkaloid |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
To gain the insight into the mechanisms underlying the effects of ZYH0005, HT29 cells and U87-MG cells were either treated with or without 100 nM of ZYH005 for 48 hours. Total RNA was extracted from these cells using Trizol (Invitrogen). Affymetrix human HTA2.0 microarrays were constructed. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-04-28 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
|
|
Dual Targeting of DNA and EGFR by ZYH005: A Novel Strategy to Induce DNA Damage and Inhibit EGFR-WEE1 Interaction in Glioblastoma Treatment
|
medRXiv
|
10.1101/2025.04.14.25325787
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
N/A
|
|
|
|
| 提交者 |
Jianzheng
Huang (2687970455@qq.com)
|
| 提交单位 |
Huazhong University of Science and Technology |
| 提交日期 |
2025-01-04 |
