| 项目编号 |
PRJCA034881 |
| 项目标题 |
The effects of antiphospholipid antibodies on macrophages and endothelial cells in vitro |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
To explore the effects of antiphospholipid antibodies (aPLs) on macrophages and endothelial cells. We extracted aPL-IgG from the serum of obstetric antiphospholipid syndrome patients and stimulated the cultured macrophages and endothelial cells using the aPL-IgG and beta 2 glycoprotein I complex in vitro. RNA of these cells was extracted for mRNA sequencing. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-06-01 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40776470
|
Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution
|
Advanced Science
|
10.1002/advs.202503480
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Sichuan Province Science and Technology Department
|
|
2022ZYD0067
|
|
|
|
| 提交者 |
Rui
Gao (kaojui@yeah.net)
|
| 提交单位 |
West China Second University Hospital |
| 提交日期 |
2025-01-10 |
