| 项目编号 |
PRJCA035695 |
| 项目标题 |
Lymph Nodes Molecular Subtypes |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
Genome sequencing
Single cell sequencing
Clinical information
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Lymph nodes (LNs) play a pivotal role in colorectal cancer (CRC) progression and immunity, yet their molecular and functional diversity remains poorly understood. By analyzing 630 LNs and 88 primary tumors from 200 CRC patients across four independent cohorts using bulk and single-cell RNA sequencing, we further found LNs heterogeneity. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-07-30 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40846857
|
Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer
|
Nature Communications
|
10.1038/s41467-025-63200-z
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
Young Scientists Fund
|
2022YFC2505700
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82100598
|
|
| Beijing Physician Scientist Training Project
|
|
BJPSTP-2024-02
|
|
|
|
| 提交者 |
Xishan
Wang (wxshan_1208@126.com)
|
| 提交单位 |
National Cancer Center, China |
| 提交日期 |
2025-02-02 |
