| 项目编号 |
PRJCA037750 |
| 项目标题 |
ANK Deficiency-Mediated Cytosolic Citrate Accumulation Promotes Aortic Aneurysm |
| 涉及领域 |
Medical |
| 数据类型 |
Epigenomics
Transcriptome or Gene expression
|
| 物种名称 |
Rattus norvegicus
|
| 描述信息 |
To obtain deeper insight into the underlying mechanisms linking ANK to the pathogenesis of AA, high-throughput RNA-sequencing of ANK-deficient rat VSMCs via small interfering RNA was performed. A total of 972 upregulated differentially expressed genes (DEGs) were identified in ANK-deficient rat VSMCs, and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis presented several pathways highly related to inflammation and energy metabolism |
| 样品范围 |
Synthetic |
| 发布日期 |
2025-03-25 |
| 出版信息 |
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
|
2019YFA0801600
|
|
|
|
| 提交者 |
Wei
Kong (kongw@bjmu.edu.cn)
|
| 提交单位 |
Peking University |
| 提交日期 |
2025-03-25 |
