| 项目编号 |
PRJCA038237 |
| 项目标题 |
Changes in brain and metabolism following tooth loss |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Metabonomics
|
| 物种名称 |
Mus musculus
|
| 描述信息 |
The study found significant disruptions in gut microbiota following tooth loss. Corresponding shifts in systemic metabolism were observed, along with changes in brain gene expression, particularly in genes related to neuroinflammation. Correlations between alterations in gut microbiota, serum metabolites, and brain gene expression were identified. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-11-04 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 41043307
|
Tooth Loss-Induced Gut Dysbiosis Promotes Neuroinflammation via L-Asparagine-Mediated Neuronal Toxicity
|
International Dental Journal
|
10.1016/j.identj.2025.103929
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| No funding support
|
|
|
|
|
|
| 提交者 |
WEI
WEI (hxkqww@163.com)
|
| 提交单位 |
Capital Medical University |
| 提交日期 |
2025-04-06 |
