| 项目编号 |
PRJCA038483 |
| 项目标题 |
A Hiplot-based web service for cold atmospheric plasma high-throughput data integration and analysis on breast cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Whole genome sequencing
Transcriptome or Gene expression
Proteome
Phosphorylome Acetylome Lactylome
|
| 物种名称 |
Mus
|
| 描述信息 |
Cold atmospheric plasma (CAP) has demonstrated selective targeting of transformed cells, but comprehensive molecular data and analysis tools for cancer applications are limited. This study addresses this gap by generating multi-omics data (transcriptome, proteome, phosphorylome, acetylome, and lactylome) from CAP-treated breast cancer cells. We developed CAPmed-BC (https://capbc.hiplot.com.cn), the first multi-omics platform in plasma medicine for analyzing breast cancer responses to CAP. The platform enables analysis of differentially expressed biomarkers, pathway enrichment, protein-protein interactions, and metabolic vulnerabilities through integrated omics. It also includes customizable visualization tools. CAPmed-BC provides a valuable resource for understanding CAP's molecular effects and advancing research in plasma medicine and oncology. |
| 样品范围 |
Monoisolate |
| 发布日期 |
2025-04-17 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
|
|
A Hiplot‐based web service for cold atmospheric plasma high‐throughput data integration and analysis on breast cancer
|
iMeta
|
10.1002/imt2.70045
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
81972789
|
Study on the Effect and Mechanism of Cold Atmospheric Pressure Plasma (CAP) in Selectively Killing Triple-Negative Breast Cancer Cells by Targeting Tumor Stemness
|
|
|
| 提交者 |
Xiaofeng
Dai (xiaofengteam@163.com)
|
| 提交单位 |
Xi'an Jiaotong University |
| 提交日期 |
2025-04-10 |
