| 项目编号 |
PRJCA038693 |
| 项目标题 |
Biomarker Identification for Predicting Response to Neoadjuvant Chemotherapy in Esophageal Squamous Cell Carcinoma |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Raw sequence reads
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Neoadjuvant chemotherapy (NACT) is a key therapeutic strategy for esophageal squamous cell carcinoma (ESCC), offering significant improvements in patient prognosis and 5-year survival rates.However, a substantial proportion of patients exhibit resistance to NACT and consequently derive limited benefit. Identifying reliable biomarkers to predict individual responses to NACT remains a critical challenge.We performed comprehensive transcriptomic profiling of tumor tissues from NACT-treated patients, stratified as responders (TRG0, 1) and non-responders (TRG2, 3), aiming to identify biomarkers associated with chemotherapy sensitivity and resistance in ESCC. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-11-03 |
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
|
82073075
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82203290
|
|
|
|
| 提交者 |
Xiang
Li (xli@hci-cn.org)
|
| 提交单位 |
China-US (Henan) Hormel Cancer Institute |
| 提交日期 |
2025-04-14 |
