| Accession |
PRJCA039957 |
| Title |
Intermittent fasting exacerbates colon inflammation by promoting Th17 cell differentiation through inhibition of gut microbiota-derived Indoleacrylic acid |
| Relevance |
Medical |
| Data types |
metabonomics
|
| Organisms |
Mus
|
| Description |
Prepare fecal samples randomly for analysis. Process data using SubstraTIQ QI software (v2.3) with parameters set to a precursor tolerance of 5 ppm, product tolerance of 10 ppm, and a production threshold of 5%. Identify compounds by comparing with databases such as HMDB, LipidMap (V2.3), and Metlin. Construct positive and negative ion mode data matrices, import into R software for principal component analysis (PCA) to evaluate sample distribution and analysis stability. Further use OPLS-DA and PLS-DA to identify group differences in metabolites. |
| Sample scope |
Multiisolate |
| Release date |
2025-05-09 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 40539205
|
Intermittent fasting exacerbates colon inflammation by promoting Th17 cell differentiation through inhibition of gut microbiota-derived indoleacrylic acid
|
World Journal of Gastroenterology
|
10.3748/wjg.v31.i22.108815
|
2025
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| university research project
|
|
2022AH051171
|
|
|
|
| Submitter |
Rui
fu (furui0008@163.com)
|
| Organization |
First Affiliated Hospital of Anhui Medical University |
| Submission date |
2025-05-09 |
